![]() The MacTel project is an international observational clinical study designed to evaluate the structural and functional changes associated with MacTel type 2 over a 5-year period. The condition that we evaluated in this study is MacTel type 2, either the nonproliferative type or the proliferative type in which neovascularization is present. These patients are primarily male, with unilateral disease. ![]() Type 1 MacTel, is considered to be aneurysmal, with dilated retinal capillaries easily detected clinically in the macular area, and fluorescein leakage is readily evident. 5 This group of diseases is now referred to as MacTel types 1 and 2. 2, 3 and recently was revised by Yannuzzi et al. Its classification was reported originally by Gass et al. The pathogenesis of the disease is unknown. As the disease progresses, intraretinal pigment plaques and subretinal neovascularization may develop. ![]() The maculae of these patients exhibit retinal juxtafoveolar telangiectasia, minimal exudation, superficial retinal crystalline deposits, and right-angle venules. ![]() The disease is typically diagnosed in the fifth or sixth decade of life. Visual acuity at presentation usually ranges from 20/25 to 20/40, although vision as poor as 20/200 may occur. Macular telangiectasia (MacTel) type 2, a type of idiopathic MacTel, 1 – 4 is an uncommon condition of bilateral irregular capillary dilation and incompetence in the macula.
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